Myndtec Inc

Empowering Patients Through Innovation!

Clinical Evidence

The efficacy of MyndMoveTM therapy is supported by numerous clinical studies, including randomized controlled trials in both stroke and spinal cord injury populations.

MyndMoveTM is the culmination of years of laboratory and clinical research by Dr. Milos Popovic, Toronto Rehab Chair in Spinal Cord Injury Research at the Toronto Rehab Institute - University Health Network, and professor at the Institute of Biomaterials and Biomedical Engineering at the University of Toronto.

Three randomized control studies, two looking at SCI and one looking at stroke patients, examined the effect of FES therapy using the MyndMoveTM protocols. These studies found that patients who underwent 40 one-hour long sessions, 3-5 times per week over an 8-12 week period, demonstrated significant and lasting recovery of voluntary arm and hand movement. Patients participating in these studies represented those with some of the most severe deficits in motor function.

Studies have demonstrated the effectiveness of MyndMoveTM protocols as FES therapy to improve hand and arm function in:

  • individuals with C3-C7 incomplete SCI
  • individuals with severe hemiplegia due to stroke

Studies evaluated improved hand and arm function based on:

  • Self-Care Functional Independence Measure (FIM) scores
  • Spinal Cord Independence Measures (SCIM) scores
  • Fugl-Meyer Assessment of Motor Recovery after stroke (FMA) scores
Videos highlighting patients participating in this research have been prepared by UHN and the Rehabilitation Engineering Laboratory.

Ongoing Studies

An ongoing open-label study and an upcoming randomized control study will assess the clinical and health-economic benefits of MyndMoveTM

Current studies using MyndMoveTM are posted on https:/

Stroke Rehabilitation

Studies have demonstrated that FES therapy using MyndMoveTM protocols can lead to lasting recovery of upper extremity function in individuals who have experienced stroke, including:

  • children
  • severe hemiplegia after acute stroke
  • severe chronic hemiplegia due to stroke

Individuals experiencing severe upper extremity paralysis who were 2-7 weeks post-acute stroke took part in the study. 7,8 The patients that underwent one hour sessions of FES therapy with MyndMoveTM 5 days a week for 12-16 weeks improved significantly more than patients undergoing conventional occupational therapy for the same timeframe in:

  • Object manipulation, palmar grip torque, pinch grip pulling force (P<0.05)
  • Barthel Index (P<0.05)
  • Self-Care Functional Independence Measure (pictured) (P=0.005)
  • Upper extremity Fugl-Meyer scores (P=0.003)

Self-Care Functional Independence Measure (SC-FIM)

Self-Care Functional Independence Measure (FIM) measures an individual’s ability to feed, bathe, dress, groom, and toilet themselves after stroke. Minimum scores are 6, which indicates full dependence, maximum scores are 42 which indicates full independence.

SCI Rehabilitation

Studies have demonstrated that FES therapy using MyndMoveTM protocols can lead to lasting recovery of upper extremity function in individuals with SCI, including:

  • chronic incomplete SCI
  • subacute incomplete SCI
  • C3-C7 SCI

Individuals experiencing upper extremity paralysis due to SCI who underwent 40 hours of FES therapy with MyndMoveTM + 40 hours of conventional occupational therapy (COT) over an 8 week period improved significantly more than patients who underwent 80 hours of COT during the 8 week period. 1,5 The patients were treated 5 days per week over the 8 week period. The difference in the mean change in SCIM self-care subscores from baseline to post treatment was statistically significant for the FES + COT group when compared to the COT only group (P< 0.0001).

Spinal Cord Independence Measure (SCIM) Self-Care Subscore


SCIM self-care subscore measures an individual’s ability to feed, bathe, dress, groom and toilet themselves. The minimum score is 0 (dependent) and the maximum score is 20 (independent).

In this study, FES therapy with MyndMoveTM delivered by therapists effectively increased independence and thereby improved the quality of life of individuals with tetraplegia when compared with conventional occupational therapy alone.

Studies Referenced

  1. Kapaida, N, Shaghayegh, B, Popovic, M. Influence of Different Rehabilitation Therapy Models on Patient Outcomes: Hand Function Therapy in Individuals with Incomplete SCI. The Journal of Spinal Cord Medicine. 2014:0:0-1.
  2. Kapadia N, Zivanovic V, Furlan J, Craven B.C, McGillivray C, Popovic M. Functional Electrical Stimulation Therapy for Grasping in Traumatic Incomplete Spinal Cord Injury: Randomized Control Trial. Artif Organs. 2011:35(3):212-216.
  3. Kapadia, N, Zivanovic, V, Popovic, M. Restoring Voluntary Grasping Function in Individuals with Incomplete Chronic Spinal Cord Injury: Pilot Study. Topics in Spinal Cord Injury Rehabilitation. 2013:19:4-279.
  4. Kawashima N., Popvic M, Zivanovic V. Effect of Intensive FES Therapy on Upper-Limb Motor Recovery After Stroke. Physiotherapy Canada. 2013:65(1):20-28.
  5. Popovic, M, Kapadia, N, Zivanovic, V, Furlan, J, Craven, C, McGillivray, C. Functional Electrical Stimulation Therapy of Voluntary Grasping Versus only Conventional Rehabilitation for Patients with Subacute Incomplete Tetraplegia: A Randomized Clinical Trial. Neurorehabilitation and Neural Repair. 2011:25:5-433.
  6. Popovic, M, Thrasher, T, Adams, M, Takes, V, Zivanovic, V, Tonack, M. Functional Electrical Therapy: Retraining Grasping in Spinal Cord Injury. Spinal Cord. 2006:44-143.
  7. Marquez-Chin, C., Bagher, S., Zivanovic, V., Popovic, M. Functional electrical stimulation therapy for severe hemiplegia: Randomized control trial revisited. Canadian Journal of Occupational Therapy. 2017:84(2):87-97
  8. Trasher T, Zivanovic V, Mcllroy W, Popvic M. Rehabilitation of Reaching and Grasping Function in Severe Hemiplegic Patients Using Functional Electrical Stimulation Therapy. Neurorehabilitation and Neural Repair. 2008:22:706-13.